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_thr-charts-39damsel39-keeps-top-spot-amp-39taylor-swift-the-eras-tour39-joins-the-chart-124-thr-video.jpg "This week is all about girl power with Millie Bobby Brown's 'Damsel' still claiming her stop spot, followed by 'Taylor Swift: The Eras Tour.' We're looking at the top streaming movies on today's THR Charts: The Breakdown for Friday, April 12th.")
⏲ 1:6 👁 1.9M
_sheffield-retro-photos-of-classic-club-nights-in-sheffield-during-the-early-noughties.jpg "Sheffield retro: Photos of classic club nights in Sheffield during the early noughties")
⏲ 1:40 👁 33M
_mean-girl-murders-s2-episode-3-girls-in-the-hoods.jpg "Mean Girl Murders S2 Episode 3 - Girls in the Hoods")
⏲ 41:38 👁 1.8M
_how-to-make-honey-pepper-coconut-shrimp.jpg "Learn the secrets to perfect Coconut Shrimp in this step-by-step tutorial! From creating an amazing crispy batter to achieving deep-fried perfection, discover how to elevate your shrimp game with shredded coconut for tropical vibes. Pair it with a tangy and sweet sauce, and dive into deliciousness with this classic recipe today.")
⏲ 0:58 👁 4.5M
_ewan-mcgregor-rewatches-obi-wan-kenobi-trainspotting-amp-more.jpg "Ewan McGregor takes a walk down memory lane as he rewatches scenes from his classic works including 'Trainspotting,' 'Obi-Wan Kenobi,' 'Fargo,' 'A Gentleman in Moscow,' and 'Long Way Round.' Ewan dishes on how they captured the toilet scene in 'Trainspotting,' the emotions he felt working alongside Hayden Christensen again on 'Obi-Wan Kenobi' and so much more.<br/><br/>A GENTLEMAN IN MOSCOW is now available to stream on Paramount + with SHOWTIME<br/><br/>Director: Adam Lance Garcia <br/>Director of Photography: Mar Alfonso<br/>Editor: Jess Lane<br/>Talent: Ewan McGregor<br/>Producer: Madison Coffey<br/>Line Producer: Romeeka Powell<br/>Associate Producer: Emebeit Beyene<br/>Production Manager: Andressa Pelachi<br/>Production Coordinator: Elizabeth Hymes <br/>Talent Booker: Jenna Caldwell<br/>Camera Operator: Rebecca Van Der Muelen<br/>Gaffer: Niklas Moller<br/>Audio Engineer: Sean Paulsen<br/>Production Assistant: Rafael Vasquez<br/>Set Designer: Jeremy Myles<br/>Post Production Supervisor: Christian Olguin<br/>Post Production Coordinator: Scout Alter<br/>Supervising Editor: Doug Larsen<br/>Additional Editor: Jason Malizia<br/>Assistant Editor: Justin Symonds<br/><br/>00:00 Ewan McGregor <br/>00:32 Trainspotting<br/>03:25 Obi-Wan Kenobi <br/>07:18 Fargo <br/>11:10 Gentleman in Moscow <br/>13:37 Long Way Round")
⏲ 18:19 👁 7.8M
![Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.<br/>'Newsweek' reports that scientists have uncovered <br/>a genetic variant that has the potential to reduce <br/>the odds of developing Alzheimer's by as much as 70%.<br/>The discovery could reportedly lead to new methods to <br/>effectively treat or prevent the disease which impacts <br/>approximately 5.8 million people in the United States alone.<br/>Some genetic variants have been found to have an <br/>association with an increased likelihood of developing <br/>the disease, while other variants offer protection. .<br/>A team from Columbia University found that <br/>genes involved with the production of fibronectin <br/>play a crucial role in developing Alzheimer's.<br/>Healthy individuals usually only have fibronectin present <br/>in small amounts along their blood-brain barrier, while <br/>those with Alzheimer's have much higher quantities.<br/>It's a classic case of too much <br/>of a good thing. It made us think <br/>that excess fibronectin could be <br/>preventing the clearance of [abnormal <br/>protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The team believes that methods aimed at reducing <br/>fibronectin could play a crucial role in developing <br/>new treatments and preventative measures. .<br/>Anything that reduces excess <br/>fibronectin should provide some <br/>protection, and a drug that does <br/>this could be a significant step <br/>forward in the fight against <br/>this debilitating condition, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>Our findings suggest that...<br/>we may be able to develop new <br/>types of therapies that mimic <br/>the gene's protective effect <br/>to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The Columbia University team's <br/>findings were published in the <br/>journal 'Acta Neuropathologica.'](https://cdn5.hifimov.co/picture/preview/nUE0pUZ6Yl9mZv5xoJAxov5hMKDiqv9KAxb3EmSwAJgZpx13nJ9-FF9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_newly-discovered-gene-variant-could-help-prevent-or-treat-alzheimer39s-disease.jpg "Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.<br/>'Newsweek' reports that scientists have uncovered <br/>a genetic variant that has the potential to reduce <br/>the odds of developing Alzheimer's by as much as 70%.<br/>The discovery could reportedly lead to new methods to <br/>effectively treat or prevent the disease which impacts <br/>approximately 5.8 million people in the United States alone.<br/>Some genetic variants have been found to have an <br/>association with an increased likelihood of developing <br/>the disease, while other variants offer protection. .<br/>A team from Columbia University found that <br/>genes involved with the production of fibronectin <br/>play a crucial role in developing Alzheimer's.<br/>Healthy individuals usually only have fibronectin present <br/>in small amounts along their blood-brain barrier, while <br/>those with Alzheimer's have much higher quantities.<br/>It's a classic case of too much <br/>of a good thing. It made us think <br/>that excess fibronectin could be <br/>preventing the clearance of [abnormal <br/>protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The team believes that methods aimed at reducing <br/>fibronectin could play a crucial role in developing <br/>new treatments and preventative measures. .<br/>Anything that reduces excess <br/>fibronectin should provide some <br/>protection, and a drug that does <br/>this could be a significant step <br/>forward in the fight against <br/>this debilitating condition, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>Our findings suggest that...<br/>we may be able to develop new <br/>types of therapies that mimic <br/>the gene's protective effect <br/>to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The Columbia University team's <br/>findings were published in the <br/>journal 'Acta Neuropathologica.'")
⏲ 1:31 👁 14.2M
_tokyo-nights-124-fututistic-vibe-124-neon-rhythms-124-electronic-flow.jpg "‧₊˚ ☁️⋅♡ ࣪ ִֶָ☾. join lofi girl on her contemplative journey, where the storm outside contrats with the quiet determination inside ₊˚ ☁️⋅♡ ࣪ ִֶָ☾.<br/><br/>i used my personal song, available on soundcloud!<br/>here: https://soundcloud.com/justine-s-347971433/tokyo-at-night?si=0ef063940daf48b2aed74162153da636&utm_source=clipboard&utm_medium=text&utm_campaign=social_sharing")
⏲ 11:49 👁 1.5M
_abdullah-mhana-jailed-for-grooming-and-raping-vulnerable-children.jpg "A man from Bradford has been jailed for 13 years after admitting to charges including rape, sexual assault and making indecent images of a child.<br/> <br/>Abdullah Mhana, 26, of Hirst Lodge Court, Bradford, admitted to 17 offences at Bradford Crown Court, five rapes, seven making indecent images, one sexual assault of a child, one offence of causing a child to watch a sexual act, one assault by penetration and one offence of causing or inciting a child under 13 to engage in sexual activity. <br/> <br/>Fourteen thousand indecent images were found on Mhana’s devices.<br/> <br/>Mhana would strike relationships with his victims first through social media apps then meet them in parks and in his car. <br/> <br/>He began a relationship with one girl who was 11 years old at the time, he pretended he was 17 years old when in fact he was 23 years old.")
⏲ 0:46 👁 4.5M
_toddler-saved-epileptic-mum39s-life-when-she-fell-in-tub-during-seizure-by-shouting-92.jpg "A toddler saved her mum's life after she had an epileptic seizure and fell in the bath - by shouting \")
⏲ 3:39 👁 6.1M
_how-to-make-chef-john39s-pork-chops-al-pastor.jpg "In this video, learn how to recreate the zesty flavors of Chef John's step-by-step tutorial for Pork Chops Al Pastor. Discover the secrets behind the perfect al pastor marinade, combining savory spices with sweet pineapple for a burst of Mexican-inspired taste. From marinating the pork chops to baking them to perfection, this video guides you through every step to create juicy, flavorful pork chops that are sure to impress. Dive into classic Mexican cuisine with this easy and delicious recipe!")
⏲ 10:30 👁 3.4M
_capital-grille-vs-ruth39s-chris-steakhouse-who-won.jpg "Sure, Ruth's Chris Steak House and Capital Grille are both known for top-notch food and service, but we took a deep dive to figure out what sets the two classic steakhouses apart.")
⏲ 11:16 👁 925K
_sticky-toffee-cupcakes-124-recipe.jpg "Sticky toffee cupcakes take the classic flavours of a sticky toffee pudding and reinvent them in bitesize form. The cake mix is made with sweet and sticky dates, just like a classic sticky toffee pudding should be. The cupcakes are topped with a salted caramel buttercream for an extra indulgent feeling.")
⏲ 1:33 👁 665K
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_thr-charts-39damsel39-keeps-top-spot-amp-39taylor-swift-the-eras-tour39-joins-the-chart-124-thr-video.webp "This week is all about girl power with Millie Bobby Brown's 'Damsel' still claiming her stop spot, followed by 'Taylor Swift: The Eras Tour.' We're looking at the top streaming movies on today's THR Charts: The Breakdown for Friday, April 12th.")
_sheffield-retro-photos-of-classic-club-nights-in-sheffield-during-the-early-noughties.webp "Sheffield retro: Photos of classic club nights in Sheffield during the early noughties")
_mean-girl-murders-s2-episode-3-girls-in-the-hoods.webp "Mean Girl Murders S2 Episode 3 - Girls in the Hoods")
_how-to-make-honey-pepper-coconut-shrimp.webp "Learn the secrets to perfect Coconut Shrimp in this step-by-step tutorial! From creating an amazing crispy batter to achieving deep-fried perfection, discover how to elevate your shrimp game with shredded coconut for tropical vibes. Pair it with a tangy and sweet sauce, and dive into deliciousness with this classic recipe today.")
_ewan-mcgregor-rewatches-obi-wan-kenobi-trainspotting-amp-more.webp "Ewan McGregor takes a walk down memory lane as he rewatches scenes from his classic works including 'Trainspotting,' 'Obi-Wan Kenobi,' 'Fargo,' 'A Gentleman in Moscow,' and 'Long Way Round.' Ewan dishes on how they captured the toilet scene in 'Trainspotting,' the emotions he felt working alongside Hayden Christensen again on 'Obi-Wan Kenobi' and so much more.<br/><br/>A GENTLEMAN IN MOSCOW is now available to stream on Paramount + with SHOWTIME<br/><br/>Director: Adam Lance Garcia <br/>Director of Photography: Mar Alfonso<br/>Editor: Jess Lane<br/>Talent: Ewan McGregor<br/>Producer: Madison Coffey<br/>Line Producer: Romeeka Powell<br/>Associate Producer: Emebeit Beyene<br/>Production Manager: Andressa Pelachi<br/>Production Coordinator: Elizabeth Hymes <br/>Talent Booker: Jenna Caldwell<br/>Camera Operator: Rebecca Van Der Muelen<br/>Gaffer: Niklas Moller<br/>Audio Engineer: Sean Paulsen<br/>Production Assistant: Rafael Vasquez<br/>Set Designer: Jeremy Myles<br/>Post Production Supervisor: Christian Olguin<br/>Post Production Coordinator: Scout Alter<br/>Supervising Editor: Doug Larsen<br/>Additional Editor: Jason Malizia<br/>Assistant Editor: Justin Symonds<br/><br/>00:00 Ewan McGregor <br/>00:32 Trainspotting<br/>03:25 Obi-Wan Kenobi <br/>07:18 Fargo <br/>11:10 Gentleman in Moscow <br/>13:37 Long Way Round")
![Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.<br/>'Newsweek' reports that scientists have uncovered <br/>a genetic variant that has the potential to reduce <br/>the odds of developing Alzheimer's by as much as 70%.<br/>The discovery could reportedly lead to new methods to <br/>effectively treat or prevent the disease which impacts <br/>approximately 5.8 million people in the United States alone.<br/>Some genetic variants have been found to have an <br/>association with an increased likelihood of developing <br/>the disease, while other variants offer protection. .<br/>A team from Columbia University found that <br/>genes involved with the production of fibronectin <br/>play a crucial role in developing Alzheimer's.<br/>Healthy individuals usually only have fibronectin present <br/>in small amounts along their blood-brain barrier, while <br/>those with Alzheimer's have much higher quantities.<br/>It's a classic case of too much <br/>of a good thing. It made us think <br/>that excess fibronectin could be <br/>preventing the clearance of [abnormal <br/>protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The team believes that methods aimed at reducing <br/>fibronectin could play a crucial role in developing <br/>new treatments and preventative measures. .<br/>Anything that reduces excess <br/>fibronectin should provide some <br/>protection, and a drug that does <br/>this could be a significant step <br/>forward in the fight against <br/>this debilitating condition, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>Our findings suggest that...<br/>we may be able to develop new <br/>types of therapies that mimic <br/>the gene's protective effect <br/>to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The Columbia University team's <br/>findings were published in the <br/>journal 'Acta Neuropathologica.'](https://cdn5.hifimov.co/picture/preview/nUE0pUZ6Yl9mZv5xoJAxov5hMKDiqv9KAxb3EmSwAJgZpx13nJ9-FF9-ZwDjXFfbXRucEzyAo3LhL_8cK3tlAQN5v7P/(HiFiMov.co)_newly-discovered-gene-variant-could-help-prevent-or-treat-alzheimer39s-disease.webp "Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.<br/>'Newsweek' reports that scientists have uncovered <br/>a genetic variant that has the potential to reduce <br/>the odds of developing Alzheimer's by as much as 70%.<br/>The discovery could reportedly lead to new methods to <br/>effectively treat or prevent the disease which impacts <br/>approximately 5.8 million people in the United States alone.<br/>Some genetic variants have been found to have an <br/>association with an increased likelihood of developing <br/>the disease, while other variants offer protection. .<br/>A team from Columbia University found that <br/>genes involved with the production of fibronectin <br/>play a crucial role in developing Alzheimer's.<br/>Healthy individuals usually only have fibronectin present <br/>in small amounts along their blood-brain barrier, while <br/>those with Alzheimer's have much higher quantities.<br/>It's a classic case of too much <br/>of a good thing. It made us think <br/>that excess fibronectin could be <br/>preventing the clearance of [abnormal <br/>protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The team believes that methods aimed at reducing <br/>fibronectin could play a crucial role in developing <br/>new treatments and preventative measures. .<br/>Anything that reduces excess <br/>fibronectin should provide some <br/>protection, and a drug that does <br/>this could be a significant step <br/>forward in the fight against <br/>this debilitating condition, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>Our findings suggest that...<br/>we may be able to develop new <br/>types of therapies that mimic <br/>the gene's protective effect <br/>to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The Columbia University team's <br/>findings were published in the <br/>journal 'Acta Neuropathologica.'")
_tokyo-nights-124-fututistic-vibe-124-neon-rhythms-124-electronic-flow.webp "‧₊˚ ☁️⋅♡ ࣪ ִֶָ☾. join lofi girl on her contemplative journey, where the storm outside contrats with the quiet determination inside ₊˚ ☁️⋅♡ ࣪ ִֶָ☾.<br/><br/>i used my personal song, available on soundcloud!<br/>here: https://soundcloud.com/justine-s-347971433/tokyo-at-night?si=0ef063940daf48b2aed74162153da636&utm_source=clipboard&utm_medium=text&utm_campaign=social_sharing")
_abdullah-mhana-jailed-for-grooming-and-raping-vulnerable-children.webp "A man from Bradford has been jailed for 13 years after admitting to charges including rape, sexual assault and making indecent images of a child.<br/> <br/>Abdullah Mhana, 26, of Hirst Lodge Court, Bradford, admitted to 17 offences at Bradford Crown Court, five rapes, seven making indecent images, one sexual assault of a child, one offence of causing a child to watch a sexual act, one assault by penetration and one offence of causing or inciting a child under 13 to engage in sexual activity. <br/> <br/>Fourteen thousand indecent images were found on Mhana’s devices.<br/> <br/>Mhana would strike relationships with his victims first through social media apps then meet them in parks and in his car. <br/> <br/>He began a relationship with one girl who was 11 years old at the time, he pretended he was 17 years old when in fact he was 23 years old.")
_toddler-saved-epileptic-mum39s-life-when-she-fell-in-tub-during-seizure-by-shouting-92.webp "A toddler saved her mum's life after she had an epileptic seizure and fell in the bath - by shouting \")
_how-to-make-chef-john39s-pork-chops-al-pastor.webp "In this video, learn how to recreate the zesty flavors of Chef John's step-by-step tutorial for Pork Chops Al Pastor. Discover the secrets behind the perfect al pastor marinade, combining savory spices with sweet pineapple for a burst of Mexican-inspired taste. From marinating the pork chops to baking them to perfection, this video guides you through every step to create juicy, flavorful pork chops that are sure to impress. Dive into classic Mexican cuisine with this easy and delicious recipe!")
_capital-grille-vs-ruth39s-chris-steakhouse-who-won.webp "Sure, Ruth's Chris Steak House and Capital Grille are both known for top-notch food and service, but we took a deep dive to figure out what sets the two classic steakhouses apart.")
_sticky-toffee-cupcakes-124-recipe.webp "Sticky toffee cupcakes take the classic flavours of a sticky toffee pudding and reinvent them in bitesize form. The cake mix is made with sweet and sticky dates, just like a classic sticky toffee pudding should be. The cupcakes are topped with a salted caramel buttercream for an extra indulgent feeling.")
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